Thursday, November 28, 2019

American Revolution or Evolution free essay sample

Doesnt it enthrall one that a single word could bifurcate scholars and create factions amongst the erudite. Tort quo © (why? ) there must be a reason and there is! The answer is simple yet rational: Perspective. Albert Einstein, (the famous physicist) most remembered by his theory of relativity, concluded that distance and time were not absolute. History resides In the same niche. It Is more than a chronological account of past events of a period or a livelihood or development of a people, an institution, or a place. But what it is not is absolute. It is always left upon interpretation, scrutiny, analysis, probing and pondering. The perception or perspective gained through such rigorous processes is also subject to the base of a historian. It Is very uncommon to find historians sharing their bases of initial learning and therefore the effect of their own era, age, surroundings and upbringing must also be taken account of. We will write a custom essay sample on American Revolution or Evolution or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page A revolution, defined by Encyclopedia Britannica Is: a major. Sudden, and hence typically a violent alteration in government and in related associations and structures.On the other hand Oxford dictionary defines an evolution as: the gradual development of something, especially from a simple to a more complex form. Let us decide upon the usage of the word Revolution, which one can venture out to say, could be dated from the year 1775 with Its Ignition being the battle of Lexington and Concord and culmination being the ratification of the constitution of the states In 1782. Seemingly easy doesnt It? It doesnt really respond to how fundamentally did the thoughts, ideals, ideology and mindset of a 2. 5 million inhabitants change and led to the chain of events that became known as the American Revolution.What I believe Is that no people In the course of history have ever rebelled against a certain state, condition or Ideology without a buildup of grievances, resentment or a gradual shift of attitude towards accepting a better sadomasochism. Lets go back to the early 17th century when immigrations began to take place into the New World. Herds of folks comprising of German, Irish, Scottish, Welsh, Jewish descent and not to mention the French Hugeness, began pouring into the lands in order to escape from the fetters of the Old World.They did not have any more an appetite for its rituals, its citrines, Its curbing of call liberties, and mostly the cost of living In It, One can even of the aforementioned causes. So it would be appropriate to say that a 17th ce ntury Europe was in revolution. Lets go further with this theory and say that the immigrants reaching the New World were revolutionaries. Almost 1 50 years of Paxar Americana (used strictly in context with the time period and not according to current usage) so to say was enjoyed by the colonists. During this time, some changes irrevocably did take place.This is evident from the fact that the language that the sorority of the immigrants originally spoke had evolved into a different dialect. So from this we can also entrust upon the belief that alongside linguistics political and socio-economic changes did also take place. A political change that actually began with the migrations was the rise of a political ideology known as Republicanism. Technically ruled by Great Britain or more accurately looked over, the colonies practiced the policy through their town halls and city councils. Very famous examples of such republican instruments were the Virginia House of Burgesses and theMassachusetts Assembly. These were regulated by either representative or direct democracy. The symbol of democracy at the time was looked upon as the House of Commons in England, however it did seem a bit more than contradicting to have the Bucking Palace towering high in the very country. The colonists did give their allegiances to the monarch but because of the fact that it was kind of conditional. Although they did not realize it nor was it formally declared but they remained docile because they were never tampered by British legislations.They had during this time, rated their own principles, created their own system of Jurisprudence, law, Justice, methods of trade, commerce, education, agriculture etc. When after the French and Indian war, the British began actively participating in the earlier enumerated colonial components of society; it wouldve obviously been not received glad hand edly by the Colonists as it did not. Lets now examine the economic evolution that took place to ensure Americas Independence. The 150 year old period was in terms of trade and commerce coined as a period of salutary neglect.For the colonists it brought economic prosperity and industrialization. For the British it was shooting themselves in the foot. Intentional lax in order to show the appreciation for economic freedom while regulating the policy of mercantilism. Does it make any sense? One would question Robert Walpole sanity between all of this; however he is not our subject of concern. What you shall so sow so shall you reap; a very old and passed around saying isnt it? But it does make sense in the context. The British for a very long period of time followed the policy and he colonist enjoyed its benefits.Smuggling was nothing out of the blue, very common. Other European nations also benefited from it, the Colonial agriculture products such as hay, wheat, barley, maize and cotton were valued highly in foreign markets. When the British annoyed at Colonial stubbornness to pay taxes, passed the writs of assistance; there was an outrage. There had to be one, like it did, smuggling was not put up with anymore and a flow of revenue generation created as a result of foreign trade stagnated. How were the merchants to run their businesses without the redeem of trading being allowed to them as it had always been?Hence there was an outcry by the merchants who went bankrupt as a result of such legislation. Somewhere or another. The country was not at all familiar with taxes; once again it is necessary to mention that when we talk about being not being tampered for almost 150 years it is meant more than it sounds. Citizens in Britain were obliged to pay taxes, however their brethren in the New World were not. I do at times believe that absolute freedom corrupts absolutely, there should be some harnesses or bridles put n in order to let civility root in or in this case for rule to sustain.When suddenly exposed to direct taxes such as Stamp Act and Sugar Acts why would it not cause havoc with in the colonists? It would lead to acrimony towards the crown like it did, it would lead to mass protests like it did and would lead to severing of ties like it did. In the beginning I wrote about how a historical event is subject to independent interpretation. How historians may or may not agree on something because of the different elements molding the shape of the basis for their knowledge.I must confess that it is no t arbitrary and applies to myself as it does to any other individual. I believe that evolution without revolution is lame and revolution without evolution blind, very similar to what Einstein said about religion and science. One thing is for certain though, nothing is by nature revolutionary. There has to be friction to beget fire. During the 150 year period evolutionary changes in political beliefs, social policies and economic mechanisms did take place otherwise the colonists wouldve never armed themselves to teeth and hoisted the flag of revolution.

Sunday, November 24, 2019

Vascular Dementia Essays

Vascular Dementia Essays Vascular Dementia Paper Vascular Dementia Paper Background Vascular dementia is the second most common form of dementia after Alzheimer disease (AD). The condition is not a single disease; it is a group of syndromes relating to different vascular mechanisms. Vascular dementia is preventable; therefore, early detection and an accurate diagnosis are important. Patients who have had a stroke are at increased risk for vascular dementia. Recently, vascular lesions have been thought to play a role in AD. As early as 1899, arteriosclerosis and senile dementia were described as different syndromes. In 1969, Mayer-Gross et al described this syndrome and reported that hypertension is the cause in approximately 50% of patients. In 1974, Hachinski et al coined the term multi-infarct dementia. In 1985, Loeb used the broader term vascular dementia. Recently, Bowler and Hachinski introduced a new term, vascular cognitive impairment. Pathophysiology Many subtypes of vascular dementia have been described to date. The spectrum includes (1) mild vascular cognitive impairment, (2) multi-infarct dementia, (3) vascular dementia due to a strategic single infarct, (4) vascular dementia due to lacunar lesions, (5) vascular dementia due to hemorrhagic lesions, (6) Binswanger disease, (7) subcortical vascular dementia, and (8) mixed dementia (combination of AD and vascular dementia). Vascular dementia is sometimes further classified as cortical or subcortical dementia. Vascular disease produces either focal or diffuse effects on the brain and causes cognitive decline. Focal cerebrovascular disease occurs secondary to thrombotic or embolic vascular occlusions. Common areas of the brain associated with cognitive decline are the white matter of the cerebral hemispheres and the deep gray nuclei, especially the striatum and the thalamus. Hypertension is the major cause of diffuse disease, and in many patients, both focal and diffuse disease are observed together. The 3 most common mechanisms of vascular dementia are multiple cortical infarcts, a strategic single infarct, and small vessel disease. Mild vascular cognitive impairment can occur in elderly persons. It is associated with cognitive decline that is worse than expected for age and educational level, but the effects do not meet the criteria for dementia and are not associated with vascular risk factors or evidence of silent strokes or extensive white matter infarcts on CT scanning. These people have subjective and objective evidence of memory problems, but their daily functional living skills are within normal limits. In multi-infarct dementia, the combined effects of different infarcts produce cognitive decline by affecting the neural nets. In single-infarct dementia, different areas in the brain can be affected, which may result in significant impairment in cognition. This may be observed in cases of anterior cerebral artery infarct, parietal lobe infarcts, thalamic infarction, and singular gyrus infarction. Small vessel disease affects all the small vessels of the brain and produces 2 major syndromes, Binswanger disease and lacunar state. Small vessel disease results in arterial wall changes, expansion of the Virchow-Robin spaces, and perivascular parenchymal rarefaction and gliosis. Lacunar disease is due to small vessel occlusions and produces small cavitary lesions within the brain parenchyma secondary to occlusion of small penetrating arterial branches. These lacunae are found more typically in the internal capsule, deep gray nuclei, and white matter. Lacunar state is a condition in which numerous lacunae, which indicate widespread severe small vessel disease, are present. Binswanger disease (also known as subcortical leukoencephalopathy) is due to diffuse white matter disease. In Binswanger disease, vascular changes observed are fibrohyalinosis of the small arteries and fibrinoid necrosis of the larger vessels inside the brain. In cerebral amyloid angiopathy–associated vasculopathy, aneurysm formation and stenosis in the leptomeningeal and cortical vessels cause damage to the subcortical white matter. In hereditary cystatin-C amyloid angiopathy, patients have recurrent cerebral hemorrhages before age 40 years that can lead to dementia. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy is a rare autosomal dominant condition localized to chromosome arm 19q12 that affects small vessels supplying the deep white matter. Pathologically, multiple small infarcts are observed in the white matter, thalamus, basal ganglia, and pons. Other less common syndromes may lead to vascular dementia. Rare arteriopathies such as inflammatory arteriopathy (eg, polyarteritis nodosa, temporal arteritis) and noninflammatory arteriopathy (eg, moyamoya disease, fibromuscular dysplasia) can cause multiple infarcts and can lead to vascular dementia. Hypoperfusion due to large vessel or cardiac disease can affect the watershed areas of the brain and lead to vascular dementia. Leukoaraiosis  greater than  25%  is considered to be pathological. Subcortical vascular dementia  is a diffuse  small vessel disease with minimal or absent infarction with  homogenous pathological and clinical features. Mixed dementia is diagnosed when patients have evidence of Alzheimer dementia and cerebrovascular disease, either clinically or based on neuroimaging evidence of ischemic lesions. Growing evidence indicates that vascular dementia and Alzheimer dementia often coexist, especially in older patients with dementia. Autopsy studies have shown the association between AD and vascular lesions.3 Several recent studies also suggest that the risk of developing AD is increased when a patient is exposed to vascular risk factors such as hypertension, diabetes mellitus, peripheral arterial disease, and smoking, which usually are associated with cerebrovascular disease and vascular dementia. Recent evidence suggests that the vascular processes in both disorders may mutually induce each other. Apolipoprotein E may play a role in AD and vascular dementia. Apolipoprotein E-IV also increases the risk of dementia in stroke survivors and is a strong risk factor for the development of cerebral amyloid angiopathy in patients with AD. In elderly individuals, many cases of dementia may be caused by the cumulative effect of cerebrovascular and Alzheimer pathology. One-third of patients with vascular dementia are found to have significant Alzheimer disease pathology with cholinergic deficits in the nucleus basalis of Meynert. Vascular cognitive disorder (VCD) is a new term used to describe a particular constellation of cognitive and functional impairment spectrum that  ranges from vascular cognitive impairment (VCI) to  subcortical vascular dementia, poststroke dementia, and mixed dementia.2 Medical Care The mainstay of management of vascular dementia is the prevention of new strokes. This includes administering antiplatelet drugs and controlling major vascular risk factors. Aspirin has also been found to slow the progression of vascular dementia. Recent guidelines from the American Psychiatric Association provide both treatment principles and possible specific therapies. Drug treatment is primarily used to prevent further worsening of vascular dementia by treating the underlying disease such as hypertension, hyperlipidemia, and diabetes mellitus. Antiplatelet agents are indicated. Pentoxifylline and, to a more limited extent, ergoloid mesylates (Hydergine), may be useful for increasing cerebral blood flow. In the European Pentoxifylline Multi-Infarct Dementia Study, which is a double-blinded, placebo-controlled, multicenter study, treatment with pentoxifylline was found to be beneficial for patients with multi-infarct dementia. Significant improvement was observed in the scales used for assessing intellectual and cognitive function. Neuroprotective drugs such as nimodipine, propentofylline, and posatirelin are currently under study and may be useful for vascular dementia. Increasing evidence supports the involvement of the cholinergic system in vascular dementia, similar to that seen in Alzheimer dementia. However, no cholinesterase inhibitors have been approved to date for the treatment of vascular dementia, despite positive results in clinical trials with this medication. The general management of dementia includes appropriate referral to community services, judgment and decision-making regarding legal and ethical issues (eg, driving, competency, advance directives), and consideration of caregiver stress. Diet In the Rotterdam study, an increased risk of vascular dementia was associated with total fat intake, whereas fish consumption was inversely related to dementia. Low levels of folate, vitamin B-6, and vitamin B-12 are associated with increased homocysteine levels, a risk factor for stroke.

Thursday, November 21, 2019

English 101 Essay Example | Topics and Well Written Essays - 500 words - 3

English 101 - Essay Example This provided her both with few playmates and multiple teachers, so that she learned to read, write and compute mathematics early and without apparent effort. However, she credits the youngest of her older brothers for the life-giving lessons of how to sit a wild horse on a wild ride in the middle of a battlefield. â€Å"Sometimes, in later yeas, when I found myself suddenly on a strange horse in a trooper’s saddle, flying for life or liberty in front of pursuit, I blessed the baby lessons of the wild gallops among the beautiful colts† (Barton, 1907: 20). After a relatively common childhood for her time period, marked by particular attention to her education thanks to the influence of brothers and sisters, Clara’s first brush with the field of nursing came as she was helping her brother, David Barton, recover from a fall that had him incapacitated for approximately 2 years (Barton, 1907: 79-88). From this experience, the young girl began moving ever closer to the nursing profession. Following the Battle of Bull Run near the beginning of the Civil War, Barton began her work as a nurse, organizing the collection and distribution of necessary medical supplies and gaining permission to ride behind the lines and in the mobile ambulance wagons to provide medical assistance to wounded soldiers on the field. Her tireless efforts earned her the nickname of ‘Angel of the Battlefield’ and she was eventually appointed the superintendent of nurses in 1861. By 1869, though, she was taking her skills to Europe to help in the Franco-Prussian War. It was in Switzerland that she first learned of the European organization already in existence there called the Red Cross. Although an attempt had already been made to establish a branch in the United States well before Barton went to Europe, this was her first time to hear of it and she spent the rest of her time in Europe learning more about it. When